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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63982 | Anticancer agent 50 | ||
Anticancer agent 50 (compound 6) is a potent modulator of the ABCB1 efflux pump with cytotoxic and anti-proliferative activity. anticancer agent 50 reduces the expression of cyclin D1 and induces p53 expression. anticanc... | |||
T60314 | Anticancer agent 38 | ||
Anticancer agent 38 (compound 19) is an aryl-urea compound, and is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC 50 of 5.2 μg/mL [1]. | |||
T63159 | Anticancer agent 28 | ||
Anticancer agent 28 showed good anti-tumour effects in vivo in H22 allograft mice. anticancer agent 28 was 50 times more potent than Oridonin against K562 cells with an IC50 value of 0.09 μM. | |||
T72468 | Anticancer agent 25 | ||
Anticancer agent 25 demonstrates the highest level of cytotoxic effectiveness on PC3 cells, achieving an IC 50 value of 0.19 μM. | |||
T61461 | Anticancer agent 37 | ||
Anticancer agent 37 (compound 18) is a sulfonylurea derivative known for its potent anticancer activity. It efficiently inhibits the growth of HePG2 cells, displaying an IC 50 value of 17.2 μg/mL [1]. | |||
T61602 | Anticancer agent 35 | ||
Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 35 inhibits A549, A431, PACA2 cell growth with IC 50 s of 18.1 μg/mL, 4.0 μg/mL, 18.9 μg/mL, respectively [1]. | |||
T61823 | Anticancer agent 63 | ||
Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC 50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 2... | |||
T61582 | Anticancer agent 57 | ||
Anticancer agent 57 (compound 14) demonstrates potent inhibition of MDA-MB-231, MDA-MB-468, and MCF-7 cell lines, with IC 50 values ranging from 6.43 to 8.00 μM. Additionally, this agent induces cell cycle arrest and pro... | |||
T83009 | Antitumor agent-107 | ||
Antitumor agent-107 (compound 5h) is an anticancer agent that exhibits potent inhibitory activity against leukemia cell lines (GI 50 =0.32-1.34 μM), and demonstrates broad-spectrum antitumor effects across a range of oth... | |||
T12434 | PF-2771 | Kinesin | |
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an anticancer agent. | |||
T72476 | Anticancer agent 59 | ||
Anticancer agent 59, an inhibitor active against various cancer cell lines, particularly demonstrates efficacy in A549 cells with an IC 50 value of 0.2 μM. It prompts apoptosis, elevates Ca2+ and ROS levels within cancer... | |||
T72756 | Gly-7-MAD-MDCPT | ||
Gly-7-MAD-MDCPT is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin compound, it shows cytotoxicity to various cancer cells with IC 50 values of 10-1000 nM [1] . | |||
T72544 | 4-Formylcolchicine | ||
4-Formylcolchicine, a potent anticancer agent, demonstrates cytotoxicity with IC 50 values of 1.007 µM for A549 cells, 0.128 µM for HT-29 cells, and 0.054 µM for HCT116 cells. | |||
TN1783 | Isolicoflavonol | Lipid | |
Isolicoflavonol is a potential cancer chemopreventive agent. | |||
T73403 | Aviculin | ||
Aviculin, a lignan glycoside, exhibits significant anticancer properties, particularly in inhibiting the metabolic activity of MCF-7 cells to below 50%, with an IC 50 value of 75.47 μM. It promotes apoptosis in breast ca... | |||
T60018 | NSC 694621 | ||
NSC 694621 is a potent PCAF inhibitor with an IC 50 of 5.71 μM ( PCAF/H3 1-21 ). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells that has the potential to be the new anticancer agent[1]. | |||
T60802 | Tubulin polymerization-IN-2 | ||
Tubulin Polymerization-IN-2 is a powerful anticancer agent that targets β-tubulin, exhibiting an IC 50 of 0.92 μM. It demonstrates promising efficacy against a range of cancer cell lines including leukemia, non-small cel... | |||
T79557 | Fac-[Re(CO)3(L6)(H2O)][NO3] | Apoptosis | |
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function. It exhibits cytotoxicity against prostate cancer cells with an IC50 of 5... | |||
T35680 | 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide | ||
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gr... | |||
TN4291 | Isofuranodiene | IL Receptor , NOS | |
Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting... |